Dermatology
Vitiligo Treatment (Melagenin Plus)
Unique Cuban-developed therapy for vitiligo repigmentation
Melagenin Plus is a topical medication developed in Cuba from human placental extract, designed to stimulate melanocyte proliferation and melanin production in areas of skin affected by vitiligo. It is one of Cuba's distinctive dermatological treatments, attracting patients from around the world seeking repigmentation options.
Expected Duration
2–4 weeks in Cuba, with several months of home treatment.
- 1
Dermatological assessment
Timeframe: 2–3 daysWood's lamp examination, extent mapping, autoimmune screening, and baseline photography to plan the protocol.
- 2
In-clinic initiation
Timeframe: 2–4 weeksDaily Melagenin Plus application with controlled sun exposure or phototherapy, plus detailed self-application training.
- 3
Home continuation
Timeframe: Several monthsContinue the take-home treatment protocol with periodic photographic review and remote follow-up.
Preparation
Complete dermatological evaluation
Have your vitiligo assessed for type, extent, and stability to set realistic repigmentation expectations.
Screen for autoimmune conditions
Blood tests for thyroid and other autoimmune disorders are recommended, as they can accompany vitiligo.
Plan sun protection
Bring broad-spectrum sunscreen and protective clothing; controlled sun exposure is part of the protocol but sunburn must be avoided.
Set realistic expectations
Repigmentation is gradual; recent lesions and certain body areas respond best, so discuss likely outcomes with your dermatologist.
Recovery
Apply Melagenin Plus consistently
Follow the application schedule and the controlled-sun-exposure instructions exactly as taught in the clinic.
Protect skin from sunburn
Use sunscreen on treated and untreated areas; brief controlled exposure helps, but burning worsens depigmentation.
Track progress with photos
Take consistent monthly photographs in the same lighting to monitor repigmentation and share with your team.
Manage associated conditions
Keep any autoimmune conditions (e.g., thyroid) under treatment, as they can influence vitiligo progression.
Attend periodic reassessment
Schedule follow-ups to evaluate response and adjust the protocol; consider a return visit if repigmentation stalls.
Why International Patients Choose Our Facilities
World-class Cuban institutions, pioneering biotechnology, and complete concierge care — the reasons patients from 40+ countries trust SMC Salud with their treatment.
Treating Facilities
Placental Histotherapy Center
Havana · Dermatology & Vitiligo
Specialized center developing and administering Melagenin Plus, Coriodermina, and Piloactive for vitiligo, psoriasis, and alopecia treatments.
The SMC Salud Advantage
Multilingual Patient Coordinators
Native-language coordinators in Arabic, Turkish, French, German, English, and more guide you through every step of your medical journey.
24/7 Concierge Support
Visa processing, airport reception, accommodation, interpreters, and round-the-clock coordination — every detail handled from inquiry to return home.
Pioneering Cuban Biotechnology
Access unique therapies developed by Cuba's leading research institutions — CIMAvax-EGF, Heberprot-P, Melagenin Plus — available only through Cuba's medical system.
Proven International Track Record
Decades of medical excellence with patients treated from over 40 countries, backed by WHO-recognized research institutions and experienced specialists.
Integrated Treatment & Recovery
Surgery, therapy, and rehabilitation delivered in one coordinated program by a single medical team — the Cuban model that achieves strong functional outcomes.
Cultural & Dietary Accommodation
Prayer rooms, halal and special-diet meals, and culturally aware care that honors your faith, customs, and family throughout your stay in Cuba.
Eligibility Assessment
Review the requirements below to understand what's needed for your treatment in Cuba. Check off each item as you prepare.
Treatment-specific eligibility
Melagenin Plus is indicated for patients with vitiligo seeking repigmentation. Treatment is most effective on recent lesions and certain body areas. Patients with widespread or long-standing vitiligo may still benefit but should have realistic expectations. A dermatological evaluation determines individual suitability.
Medical Documentation
Health Requirements
Travel & Logistics
Check off items as you prepare — a CTA will appear when all are reviewed.
Real Stories from Our Patients
Read firsthand accounts from international patients who completed their medical journeys with us.
“After years of unsuccessful treatments elsewhere, the Melagenin Plus therapy in Cuba gave me visible repigmentation within weeks. The dermatology team was compassionate and thorough.”
Elif Y.
Turkey
Vitiligo (Melagenin Plus)“Coriodermina transformed my skin and my confidence. The personalized care plan and follow-up exceeded everything I experienced in Europe.”
Lucía R.
Spain
Psoriasis (Coriodermina)Frequently Asked Questions
Quick Answers to Common Questions
Direct answers to the questions international patients ask most about this treatment in Cuba.
How much does Melagenin Plus treatment cost in Cuba?
Costs vary based on the extent of vitiligo, treatment duration, and take-home medication needed. SMC Salud provides a detailed cost breakdown as part of the personalized treatment proposal following the dermatological evaluation. Submit a consultation request to receive an estimate.
What currency can I pay in?
International bank transfers should be in Euros, British Pounds, or Canadian Dollars. USD transfers are not accepted. The online payment gateway accepts Visa, MasterCard, Maestro, and American Express. Cash is not accepted.
Is Melagenin Plus a cure for vitiligo?
Melagenin Plus is not a cure for vitiligo. It is a treatment that aims to stimulate repigmentation of affected skin areas. Results are gradual and vary significantly between individuals. Some patients achieve meaningful repigmentation, while others see limited improvement. Vitiligo is a chronic condition, and ongoing management is typically needed.
How is Melagenin Plus applied?
Melagenin Plus is applied topically to depigmented areas, followed by brief controlled sun exposure or phototherapy. The medication is applied daily during the in-clinic phase (2-4 weeks in Cuba), after which patients continue the protocol at home with take-home medication for several months.
Does Melagenin Plus work for all types of vitiligo?
Melagenin Plus works best for non-segmental, segmental, and focal vitiligo affecting areas with hair follicles (face, neck, trunk). Mucosal vitiligo (lips, genitals) and acral vitiligo (hands, feet) are typically resistant. The dermatology team assesses your specific case during the initial evaluation.
Is Melagenin Plus available outside Cuba?
Melagenin Plus is a Cuban-developed product available through SMC Salud's international patient services. Patients travel to Cuba to begin treatment under dermatological supervision, then continue with a take-home protocol. It may not be widely available in other countries.
Explore in-depth guides on this treatment:
Cost of Vitiligo Treatment in Cuba (Melagenin Plus)More Dermatology Treatments in Cuba
Explore related Cuban medical programs in the same specialty area.
Specialists & Medical Centers
The physicians and Cuban medical institutions behind this specialty.
Vitiligo Treatment in Cuba (Melagenin Plus) — Explore Further
clusterLinks.desc
The team that receives your request
You access our services through the Coordination and Processing Center, where a specialist immediately responds to your request and assesses whether you require the service — and you can also access an online consultation prior to your trip.
Iliana Reyes Álvarez
Head of the Coordination and Processing Center
Doctor in Medicine, First Degree Specialist in Comprehensive General Medicine. Master in Primary Health Care. Certified in Foreign Trade.
Osvaldo Héctor Ardisana
Commercial Specialist, International Medical Services
Doctor in Medicine. First Degree Specialist in Comprehensive General Medicine. Master in Marketing and Social Communication. Certified in Foreign Trade.
Natalia Hijuelos Aleexeva
Commercial Specialist, International Medical Services
Doctor in Medicine. First Degree Specialist in Comprehensive General Medicine. Certified in Nutrition and Foreign Trade.
Julio César González Palomino
Commercial Specialist, International Medical Services
Doctor in Medicine, First Degree Specialist in Comprehensive General Medicine. Master in Medical Emergencies.
Tatiana Solano López
Commercial Specialist, International Medical Services
Doctor of Medicine. First-Degree Specialist in Psychiatry. Certified in Medical Emergencies and Urgent Care. Bachelor of Science in Nursing.
Tania Bárbara Vázquez García
Commercial Specialist, International Medical Services
Bachelor's Degree in German Language and Scientific-Technical Information. Certified in Technical Information Processes, Foreign Trade, Foreign Investment, and International Cooperation.
We are here to help you with personalized, safe and high-quality medical solutions.
Contact usReady to Learn More?
Submit a consultation request and our medical team will review your case within 24–48 hours.
Request Consultation