Melagenina Plus® · Placental Histotherapy · Repigmentation
Vitiligo Treatment in Cuba
Cuba's Placental Histotherapy Center (Centro de Histoterapia Placentaria) in Havana developed Melagenina Plus, a placental-derived therapy for vitiligo that has attracted patients from over 50 countries. The treatment stimulates melanocyte replication and repigmentation through topical application combined with controlled sun exposure, offering a unique approach unavailable in most countries.
Vitiligo — Treatment Video
Cuba's Placental Histotherapy for Vitiligo
Visual Guide
Understanding vitiligo care in Cuba
See the specialized facilities and patient-centered care that define our vitiligo treatment programs.
Specialized Dermatology care in Cuba
Comprehensive international patient coordination in Havana
Clinical Evidence & Outcomes
The science behind vitiligo treatment in Cuba
Our clinical programs are grounded in peer-reviewed research and coordinated with Cuba's biotechnology institutions. Individual results vary and are confirmed during personalized evaluation.
Melagenina Plus®
Vitiligo
Melagenina Plus is a placental-derived therapy developed by Cuba's Placental Histotherapy Center. It has been used by patients from over 50 countries seeking repigmentation treatment. The therapy works by stimulating melanocyte replication in depigmented skin areas when combined with controlled sun exposure.
Source: Centro de Histoterapia Placentaria — Havana
Placental Histotherapy
Dermatological Conditions
The Placental Histotherapy Center was established in 1987 and has become a reference institution for placental-derived therapies. Its research into the regenerative properties of placental extracts has produced treatments for vitiligo and other dermatological conditions.
Source: Centro de Histoterapia Placentaria — Havana
Outpatient Treatment Model
International Patients
Treatment is administered on an outpatient basis with daily clinic visits over a 2–3 week period. Patients receive Melagenina Plus topical applications combined with controlled sun exposure, with progress monitored by dermatologists throughout the program.
Source: SMC Salud — Office of Medical Affairs
Outcomes shown reflect published clinical data and aggregate results. Individual results vary based on diagnosis, disease stage, and overall health, and are confirmed during a personalized medical evaluation. This page is for educational purposes and is not a substitute for professional medical advice.
Your Treatment Pathway
Vitiligo Care Pathway
A coordinated, step-by-step pathway from pre-travel preparation through treatment in Cuba and post-departure follow-up.
Initial Inquiry & Records Review
Submit your medical records for expert review by our specialist team. Our international coordinators respond within 24–48 hours with an initial assessment.
- Medical records submission via secure portal
- Case review by specialist medical team
- Initial eligibility assessment
Remote Medical Evaluation
Your case is reviewed by the Cuban medical team. Additional tests or imaging may be requested remotely. A personalized treatment plan is developed and shared with you and your home-country physician.
- Specialist remote consultation
- Additional diagnostics if needed
- Personalized treatment plan issued
Program Issuance & Travel Arrangements
SMC Salud issues your official medical program letter. Our coordinators assist with visa application, flight booking, and accommodation — matched to your treatment program and family needs.
- Medical program letter issued
- Visa application support
- Flight & accommodation arranged
Melagenina Plus Treatment Program
Dermatological evaluation of vitiligo type, extent (BSA involvement), and stability. Daily clinic visits for Melagenina Plus topical application combined with medically supervised controlled sun exposure.
- Dermatological evaluation & BSA mapping
- Daily Melagenina Plus application
- Medically supervised sun exposure
Repigmentation Monitoring
Photographic tracking of repigmentation progress. Psychological support for the emotional impact of vitiligo. Sun exposure guidelines and maintenance protocols provided for continued care after return home.
- Photographic repigmentation tracking
- Psychological & quality-of-life support
- Maintenance & sun exposure guidelines
Discharge, Report & Follow-up
Comprehensive medical report translated into your language. Take-home medication supply provided. Telemedicine follow-up program arranged so your Cuban medical team stays connected after you return home.
- Translated comprehensive medical report
- Take-home medication supply
- Telemedicine follow-up scheduled
Our Comprehensive Approach
Melagenina Plus®
A placental-derived extract applied topically to depigmented areas to stimulate melanocyte activity and repigmentation.
Controlled Sun Exposure
Treatment is combined with medically supervised sun exposure to activate the melanin-stimulating properties of the therapy.
Comprehensive Evaluation
Dermatological assessment of vitiligo type, extent (BSA involvement), stability, and treatment history before starting.
Outpatient Protocol
Treatment is administered on an outpatient basis with daily clinic visits, allowing patients to enjoy Havana between sessions.
Psychological Support
Counseling and support for the emotional impact of vitiligo, addressing quality of life and self-image.
International Coordination
Medical visa, accommodation, interpretation, and 24/7 support throughout the treatment program.
Vitiligo — Treatment & Medication
Treatment Options Available in Cuba
Cuba's Placental Histotherapy Center developed Melagenina Plus®, a placental-derived therapy applied topically to depigmented areas to stimulate melanocyte activity, combined with controlled sun exposure. No therapy can cure vitiligo, and not every patient will benefit. Treatment suitability is determined after a dermatological evaluation of vitiligo type, extent, and stability.
Treatment suitability is determined after medical evaluation. No therapeutic outcome is guaranteed, and not every patient will benefit. Each case is reviewed individually by the medical team.
Vitiligo — Required Documents
Documents for Medical Evaluation
Providing these documents helps our medical team review your case before you travel. You do not need to send every document to begin — send what you have available.
Skin Photographs
Clear images of depigmented areas
Dermatology Reports
Specialist assessment and diagnosis
Previous Treatment Records
Prior therapies and their outcomes
Current Medications
All medications and topical treatments used
Recent Laboratory Results
Blood work and relevant test results
Diagnosis Reports
Confirmed vitiligo diagnosis and type
Clinical Evidence
Patient Safety
Expert Specialists
International Standards
Frequently Asked Questions
Questions from international patients
Melagenina Plus is a placental-derived extract developed by Cuba's Placental Histotherapy Center. It is applied topically to depigmented skin areas to stimulate melanocyte activity and promote repigmentation. The treatment is combined with controlled sun exposure, which activates the melanin-stimulating properties of the placental extract. It was developed in Cuba and is not widely available in other countries.
Find country-specific information, testimonials, and FAQs for your region.
Could This Treatment Be Right for You?
Submit your medical records for review by our medical team. We will assess your case and provide a personalized recommendation. Treatment suitability is determined only after medical evaluation.