CIREN · Intensive Neurorehabilitation · Itolizumab Research
Multiple Sclerosis Treatment in Cuba
Cuba's International Center for Neurological Restoration (CIREN) offers intensive multidisciplinary rehabilitation programs for multiple sclerosis patients. The approach combines 4–6 hours of daily coordinated therapy across neurology, physical therapy, occupational therapy, and neuropsychology — an intensity that standard rehabilitation programs typically do not match. Cuba has also contributed to MS research through the development of Itolizumab, a monoclonal antibody studied in autoimmune conditions.
Multiple Sclerosis — Treatment Video
Cuba's Neurological Restoration — MS Rehabilitation
Visual Guide
Understanding multiple sclerosis care in Cuba
See the specialized facilities and patient-centered care that define our multiple sclerosis treatment programs.

Specialized Neurology care in Cuba

Comprehensive international patient coordination in Havana
Clinical Evidence & Outcomes
The science behind multiple sclerosis treatment in Cuba
Our clinical programs are grounded in peer-reviewed research and coordinated with Cuba's biotechnology institutions. Individual results vary and are confirmed during personalized evaluation.
CIREN Intensive Rehabilitation Model
Multiple Sclerosis
CIREN's intensive model delivers 4–6 hours of coordinated daily therapy across multiple disciplines for MS patients. The approach addresses motor symptoms, fatigue, cognitive changes, and quality of life through a team of neurologists, physiatrists, physical therapists, occupational therapists, and neuropsychologists.
Source: CIREN — International Center for Neurological Restoration
Itolizumab (Alzumab)
Autoimmune Research
Itolizumab is a monoclonal antibody developed by Cuba's Center of Molecular Immunology (CIM) targeting the CD6 receptor on T cells. It has been studied in autoimmune conditions including psoriasis and has been investigated for its immunomodulatory potential in MS and other demyelinating diseases.
Source: CIM — Center of Molecular Immunology
Multidisciplinary Care
Motor & Cognitive Symptoms
Founded in 1989, CIREN has treated thousands of international patients with neurological conditions including MS. Its model addresses both motor symptoms (weakness, spasticity, ataxia, fatigue) and cognitive symptoms (memory, attention, executive function) through coordinated daily therapy.
Source: CIREN — International Center for Neurological Restoration
Outcomes shown reflect published clinical data and aggregate results. Individual results vary based on diagnosis, disease stage, and overall health, and are confirmed during a personalized medical evaluation. This page is for educational purposes and is not a substitute for professional medical advice.
Your Treatment Pathway
Multiple Sclerosis Care Pathway
A coordinated, step-by-step pathway from pre-travel preparation through treatment in Cuba and post-departure follow-up.
Initial Inquiry & Records Review
Submit your medical records for expert review by our specialist team. Our international coordinators respond within 24–48 hours with an initial assessment.
- Medical records submission via secure portal
- Case review by specialist medical team
- Initial eligibility assessment
Remote Medical Evaluation
Your case is reviewed by the Cuban medical team. Additional tests or imaging may be requested remotely. A personalized treatment plan is developed and shared with you and your home-country physician.
- Specialist remote consultation
- Additional diagnostics if needed
- Personalized treatment plan issued
Program Issuance & Travel Arrangements
SMC Salud issues your official medical program letter. Our coordinators assist with visa application, flight booking, and accommodation — matched to your treatment program and family needs.
- Medical program letter issued
- Visa application support
- Flight & accommodation arranged
Intensive Neurorehabilitation Program
Admission to CIREN. Comprehensive baseline assessment including neurological exam, EDSS scoring, and neuroimaging. 4–6 hours of daily coordinated therapy targeting motor function, fatigue management, cognition, and quality of life.
- EDSS baseline & neuroimaging review
- 4–6 hrs daily multidisciplinary therapy
- Pharmacological management coordination
Function & Quality of Life Monitoring
Regular functional reassessment to measure progress. Energy conservation strategies, adaptive equipment recommendations, and caregiver education for relapse recognition and home program continuation.
- Functional progress reassessment
- Energy conservation & adaptive strategies
- Caregiver education & home program
Discharge, Report & Follow-up
Comprehensive medical report translated into your language. Take-home medication supply provided. Telemedicine follow-up program arranged so your Cuban medical team stays connected after you return home.
- Translated comprehensive medical report
- Take-home medication supply
- Telemedicine follow-up scheduled
Our Comprehensive Approach
Neurological Management
Personalized pharmacological plans coordinated by neurologists specialized in demyelinating diseases.
Intensive Physical Therapy
Daily therapy targeting strength, balance, coordination, gait, and fatigue management to preserve mobility.
Occupational Therapy
Strategies to maintain independence in daily activities, energy conservation, and adaptive equipment.
Speech & Swallowing Therapy
Addresses dysarthria, dysphagia, and cognitive-communication changes that can occur in MS.
Neuropsychological Support
Cognitive rehabilitation for memory, attention, and executive function, plus mood and adjustment support.
Caregiver & Family Education
Families trained to support continued rehabilitation, medication adherence, and relapse recognition at home.
Multiple Sclerosis — Treatment & Medication
Treatment Options Available in Cuba
CIREN offers intensive multidisciplinary rehabilitation for multiple sclerosis, combining daily therapy across neurology, physical therapy, occupational therapy, and neuropsychology. This is a rehabilitation program, not a disease-modifying therapy. No therapy can cure MS. Treatment suitability is determined after a medical evaluation of MS type and current functional level.
Treatment suitability is determined after medical evaluation. No therapeutic outcome is guaranteed, and not every patient will benefit. Each case is reviewed individually by the medical team.
Multiple Sclerosis — Required Documents
Documents for Medical Evaluation
Providing these documents helps our medical team review your case before you travel. You do not need to send every document to begin — send what you have available.
Brain / Spine MRI
Recent neuroimaging studies
Neurology Reports
Specialist consultation and assessment notes
Diagnosis Reports
Confirmed MS diagnosis and type
Previous Treatment Records
Prior disease-modifying therapies
Current Medication List
All medications and dosages currently taken
Recent Laboratory Results
Blood work and relevant test results
Clinical Evidence
Patient Safety
Expert Specialists
International Standards
Frequently Asked Questions
Questions from international patients
CIREN offers intensive multidisciplinary rehabilitation programs for MS patients, delivering 4–6 hours of daily coordinated therapy across neurology, physical therapy, occupational therapy, speech therapy, and neuropsychology. The program aims to improve mobility, manage fatigue, address cognitive changes, and enhance quality of life. It is a rehabilitation program, not a disease-modifying therapy.
Find country-specific information, testimonials, and FAQs for your region.
Could This Treatment Be Right for You?
Submit your medical records for review by our medical team. We will assess your case and provide a personalized recommendation. Treatment suitability is determined only after medical evaluation.

















