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Comercializadora de Servicios Médicos Cubanos, S.A.SMC Salud

CIREN · Intensive Neurorehabilitation · Itolizumab Research

Multiple Sclerosis Treatment in Cuba

Relapsing-Remitting MS · Secondary Progressive MS · Primary Progressive MS

Cuba's International Center for Neurological Restoration (CIREN) offers intensive multidisciplinary rehabilitation programs for multiple sclerosis patients. The approach combines 4–6 hours of daily coordinated therapy across neurology, physical therapy, occupational therapy, and neuropsychology — an intensity that standard rehabilitation programs typically do not match. Cuba has also contributed to MS research through the development of Itolizumab, a monoclonal antibody studied in autoimmune conditions.

Multiple Sclerosis treatment in Cuba

Multiple Sclerosis — Treatment Video

Cuba's Neurological Restoration — MS Rehabilitation

Visual Guide

Understanding multiple sclerosis care in Cuba

See the specialized facilities and patient-centered care that define our multiple sclerosis treatment programs.

Specialized Neurology care in Cuba

Specialized Neurology care in Cuba

Comprehensive international patient coordination in Havana

Comprehensive international patient coordination in Havana

Clinical Evidence & Outcomes

The science behind multiple sclerosis treatment in Cuba

Our clinical programs are grounded in peer-reviewed research and coordinated with Cuba's biotechnology institutions. Individual results vary and are confirmed during personalized evaluation.

Medically reviewed by
SMC Salud Office of Medical Affairs·Neurology·Reviewed August 7, 2026

CIREN Intensive Rehabilitation Model

Multiple Sclerosis

4–6 hrsdaily therapy, 4–8 week programs

CIREN's intensive model delivers 4–6 hours of coordinated daily therapy across multiple disciplines for MS patients. The approach addresses motor symptoms, fatigue, cognitive changes, and quality of life through a team of neurologists, physiatrists, physical therapists, occupational therapists, and neuropsychologists.

Source: CIREN — International Center for Neurological Restoration

Itolizumab (Alzumab)

Autoimmune Research

Cuban-developedanti-CD6 monoclonal antibody

Itolizumab is a monoclonal antibody developed by Cuba's Center of Molecular Immunology (CIM) targeting the CD6 receptor on T cells. It has been studied in autoimmune conditions including psoriasis and has been investigated for its immunomodulatory potential in MS and other demyelinating diseases.

Source: CIM — Center of Molecular Immunology

Multidisciplinary Care

Motor & Cognitive Symptoms

1989CIREN founded — 35+ years

Founded in 1989, CIREN has treated thousands of international patients with neurological conditions including MS. Its model addresses both motor symptoms (weakness, spasticity, ataxia, fatigue) and cognitive symptoms (memory, attention, executive function) through coordinated daily therapy.

Source: CIREN — International Center for Neurological Restoration

Outcomes shown reflect published clinical data and aggregate results. Individual results vary based on diagnosis, disease stage, and overall health, and are confirmed during a personalized medical evaluation. This page is for educational purposes and is not a substitute for professional medical advice.

Your Treatment Pathway

Multiple Sclerosis Care Pathway

A coordinated, step-by-step pathway from pre-travel preparation through treatment in Cuba and post-departure follow-up.

Pre-Travel
1

Initial Inquiry & Records Review

Week 1

Submit your medical records for expert review by our specialist team. Our international coordinators respond within 24–48 hours with an initial assessment.

  • Medical records submission via secure portal
  • Case review by specialist medical team
  • Initial eligibility assessment
2

Remote Medical Evaluation

Week 1–2

Your case is reviewed by the Cuban medical team. Additional tests or imaging may be requested remotely. A personalized treatment plan is developed and shared with you and your home-country physician.

  • Specialist remote consultation
  • Additional diagnostics if needed
  • Personalized treatment plan issued
3

Program Issuance & Travel Arrangements

Week 2–3

SMC Salud issues your official medical program letter. Our coordinators assist with visa application, flight booking, and accommodation — matched to your treatment program and family needs.

  • Medical program letter issued
  • Visa application support
  • Flight & accommodation arranged
In Cuba
4

Intensive Neurorehabilitation Program

4–8 weeks

Admission to CIREN. Comprehensive baseline assessment including neurological exam, EDSS scoring, and neuroimaging. 4–6 hours of daily coordinated therapy targeting motor function, fatigue management, cognition, and quality of life.

  • EDSS baseline & neuroimaging review
  • 4–6 hrs daily multidisciplinary therapy
  • Pharmacological management coordination
5

Function & Quality of Life Monitoring

Ongoing

Regular functional reassessment to measure progress. Energy conservation strategies, adaptive equipment recommendations, and caregiver education for relapse recognition and home program continuation.

  • Functional progress reassessment
  • Energy conservation & adaptive strategies
  • Caregiver education & home program
Post-Departure
6

Discharge, Report & Follow-up

Final days + ongoing

Comprehensive medical report translated into your language. Take-home medication supply provided. Telemedicine follow-up program arranged so your Cuban medical team stays connected after you return home.

  • Translated comprehensive medical report
  • Take-home medication supply
  • Telemedicine follow-up scheduled

Our Comprehensive Approach

Neurological Management

Personalized pharmacological plans coordinated by neurologists specialized in demyelinating diseases.

Intensive Physical Therapy

Daily therapy targeting strength, balance, coordination, gait, and fatigue management to preserve mobility.

Occupational Therapy

Strategies to maintain independence in daily activities, energy conservation, and adaptive equipment.

Speech & Swallowing Therapy

Addresses dysarthria, dysphagia, and cognitive-communication changes that can occur in MS.

Neuropsychological Support

Cognitive rehabilitation for memory, attention, and executive function, plus mood and adjustment support.

Caregiver & Family Education

Families trained to support continued rehabilitation, medication adherence, and relapse recognition at home.

Multiple Sclerosis — Treatment & Medication

Treatment Options Available in Cuba

CIREN offers intensive multidisciplinary rehabilitation for multiple sclerosis, combining daily therapy across neurology, physical therapy, occupational therapy, and neuropsychology. This is a rehabilitation program, not a disease-modifying therapy. No therapy can cure MS. Treatment suitability is determined after a medical evaluation of MS type and current functional level.

Treatment suitability is determined after medical evaluation. No therapeutic outcome is guaranteed, and not every patient will benefit. Each case is reviewed individually by the medical team.

Multiple Sclerosis — Required Documents

Documents for Medical Evaluation

Providing these documents helps our medical team review your case before you travel. You do not need to send every document to begin — send what you have available.

Brain / Spine MRI

Recent neuroimaging studies

Neurology Reports

Specialist consultation and assessment notes

Diagnosis Reports

Confirmed MS diagnosis and type

Previous Treatment Records

Prior disease-modifying therapies

Current Medication List

All medications and dosages currently taken

Recent Laboratory Results

Blood work and relevant test results

Send Your Medical Documents

Clinical Evidence

Patient Safety

Expert Specialists

International Standards

Frequently Asked Questions

Questions from international patients

CIREN offers intensive multidisciplinary rehabilitation programs for MS patients, delivering 4–6 hours of daily coordinated therapy across neurology, physical therapy, occupational therapy, speech therapy, and neuropsychology. The program aims to improve mobility, manage fatigue, address cognitive changes, and enhance quality of life. It is a rehabilitation program, not a disease-modifying therapy.

Could This Treatment Be Right for You?

Submit your medical records for review by our medical team. We will assess your case and provide a personalized recommendation. Treatment suitability is determined only after medical evaluation.